(Time) Study: How Chronic Stress Can Lead to Depression
Can chronic stress cause depression? A new study in mice adds important evidence that it can, and sheds light on how antidepressants work.
The new research, published in Nature, builds on earlier studies showing that chronic high stress kills neurons and prevents neurogenesis — or the birth of new brain cells — in a region called the hippocampus. Neurogenesis in the hippocampus seems to be necessary for a healthy stress response.
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This means that the brain responds to stress by killing brain cells, making itself more sensitive to future stress!